Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is among the cancer types with poorest prognosis and survival rates primarily due to resistance to standard-of-care therapies, including gemcitabine (GEM) and olaparib.Particularly, wild-type (wt)BRCA tumours, the most prevalent in PDAC, are more resistant to DNA-targeting agents like olap

In order to investigate the influence of multi-radiators, active scattering characteristics, which can be reflected by the active radar cross section (ARCS), are investigated by incorporating read more the multi-radiators with the radar-radiator.The proposed implementation takes advantage of the ARCS concept in terms of considerable accuracy and cl

Background.Insufficient movement patterns may expose athletes to injury, so it is vital to recognize and rectify these movement patterns.Objectives.The purpose of this study was to assess the fundamental read more movement patterns and determine the effect of a four-week FIFA+11 program on functional movement screen (FMS) scores of junior soccer pl

Whether they are nationals reporting wars occurring within their countries or international news media staff, journalists are facing growing dangers when covering conflict events.As civilians, they are protected to some extent by international humanitarian law (IHL).But what are these rules and how adequate is such coverage? The article grandpas be

Several future accelerator projects read more at Brookhaven for the Relativistic Heavy Ion Collider (RHIC) are based on energy recovery linacs (ERLs) with high-charge high-current electron beams.Their stable operation mandates effective higher-order-mode (HOM) damping.The development of HOM dampers for these projects is pursued actively at this lab